The peripheral neuropathic pain damages peripheral nerves that bring the psychics information from periphery to central nervous system (encephalon and spinal cord). Peripheral nerves are divided in psychic nerve (these receive information by sense organs and they all transmit to the central nervous system), motor nerve (these transmit information from the central nervous system to effector organs), mixed nerve (composed by both parts: psychic and motor). There are many causes about nerve diseases; these are defined on modes of occurrence, relevant fiber, pain distribution and the “damage”. It is assumed hereditary and metabolic factors, oxidative stress, inflammation and trauma.

PRODUCT NAME
Xinepa Easy®

FORMAT AND PACKAGE
Oral Sachets, 30 oral sachets. The Xinepa Easy® case has a patented “TAMPER EVIDENRT” sealing system to report the product integrity. Consult our web-site for more information.

USE INDICATIONS
Xinepa Easy® is a food supplement composed by Alpha-lipoic acid, N-acetyl-L-carnitine, curcuma, vitamins B, E and C.

• Vitamins B1, B2, B6 and B12 contribute to the nervous system and energy metabolism proper functioning.
• B2, B6, B12 help in case of tiredeness and fatigue.
• Curcuma, Vitamin C and E are cells protection factors by the oxidative stress

COMPOSITION
A Xinepa Easy® sachet includes:
N-acetyl-L-carnitine (400 mg), alpha-lipoic acid (300 mg), CurQfen® dry extract (curcuma longa L. and Trigonella foenum-graecum dry extract) that belongs to total curcuminoids (35%) (60 mg), Vitamin C (125 mg), vitamin E (9 mg), vitamin B1 (6,25 mg), vitamin B2 (6,25 mg), vitamin B6 (2,38 mg), vitamin B12 (6,25 mg).

COMPONENTS
ALPHA-LIPOIC ACID
The alpha-lipoic acid is inside our organism. It has the ability to act in aqueous and lipophilic environments. It is an antioxidant element with a strong role in cells energy metabolism. The alpha-lipoic acid synthesis by the organism decreases with the age.

N-ACETIL-L-CARNITINA
The N-acetyl-L-carnitine is available in skeletal and striated muscle. It supports the transportation and the consumption (oxidation) of long-chain fatty acids for energy production and it is active for cell and mitochondrion, and as trophic factor for cellular integrity restoration.
The alpha-lipoic acid and the N-acetyl-L-carnitine in Xinepa Easy® are characterized by an innovative technology M.A.T.R.I.S® which permits a modified-release.

CURCUMA
The CurQfen® is a curcuma extract (curcuma longa L.) standardised at 35% in curcuminoids and Trigorella foenum-graecum. This particular combination increases the absorption after the oral administration, optimizing also the low-dose effects. CurQfen® is registered brand of Akay Flavours & Aromatics Pvt. Ltd. Malaidamthuruthu P. O., Aluva, Cochin 683561, Kerala, India.

VITAMINS GROUP B: B1 + B2 + B6 + B12
The vitamins group B support the nervous system and energetic metabolism proper functioning. Vitamins B1 and B2 provide energy to nervous tissue. Vitamin B6 is essential for neurotransmitters synthesis (including the serotonin that has positive effects on mood) and myelin formation that is a protective structure for central nervous system. Vitamin B12 is important for red blood cells formation and for myelin sheaths integrity and functioning. Its lack could bring to an altered fatty acids biosynthesis, that are a structural part of myelinated upholstery. Vitamins B2 and B6 represent a great help for tiredness and fatigue decrease

VITAMIN E
It is a fat-soluble antioxidant, especially linked to cell membranes, because it protects the cell by free radicals’ damages. It helps to maintain the nervous system proper functioning, protecting blood vessel and nervous cells membranes

VITAMIN C
Vitamin C is a water-soluble antioxidant and its integration is really effective if it is accompanied by vitamin E. This vitamin has many functions. It contributes to cells protection by oxidative stress, nervous system functioning and psychological well-being. It reduces tiredness and fatigue, helping immune system functioning.

USE CONDITIONS
It is advised the consumption of 1 or 2 oral sachets a day of Xinepa Easy® after main meals. Pour directly the contents in your mouth. Dissolve the granulate without chewing. If you need, take a drink of water.

WARNINGS
Xinepa Easy® must be stored at ambient temperature (between 8° and 25° Celsius, 46,4° and 77° Fahrenheit) in dry and cool place. The expiry date is linked to the correctly stored product, in undamaged packages. Keep out of reach of children under the 3 years old. Do not exceed the recommended daily dose. The food supplements should not be seen as a substitute of a varied and balanced diet and a healthy lifestyle. If you are under treatment with hypoglycemic agents, it is advised to consult your doctor, before the product consumption. Possible product chromatic changes must be assumed as a natural phenomenon because of the occurrence of a high quantity of plant extracts. The perception of a mild discomfort during the product swallowing, is due to its composition and it is a temporary phenomenon. There are no scientific data about Xinepa Easy® use in pregnancy and breastfeeding. It is recommended to consult your doctor, especially during the first pregnancy quarter.

INFORMATION IN CASE OF FOOD INTOLLERANCE
AND/OR ALLERGIES
Xinepa Easy®:

• Has no gluten, and it can be taken by coeliac
• Has no lactose and dairy products
• Can be taken by vegetarian and vegan

Don’t use Xinepa Easy® in case of known hypersensitivity to its components.

PRODUCT CERTIFICATIONS AND DECLARATIONS

	KOSHER This validation gives to Xinepa Easy® the validity to be consumed by Jewish people, according to their religion food regulations and it is expression of the highest qualitative standards about substances used during industrial processes.
	HALAL ITALIA This validation certifies that Xinepa Easy® complies with Islamic doctrine, according to Sharia regulations. It is a validation based on the quality of chain and product substances.
	DOPING FREE This validation certifies that Xinepa Easy® does not use substances and/or ingredients present in Wada list (consult the banned substances list). The company, through a constant promotion of ethical values, wants to guarantee to clients and consumers, a permanent fight against doping substances.
	LACTOSE-MILK FREE This validation guarantees that Xinepa Easy® is a product with the complete lack of milk and it is indicated for lactose-intolerant.
	UIC All Xinepa Easy® fonts in graphic image – Braille – have been checked through the “Unione Italiana Ciechi” (Blind Italian Confederation) verification, which certified the texts correctness and quality.

NOTE
The information included in the Xinepa Easy® leaflet can’t and don’t replace your doctor’s advice, but these want to represent an orientation and consultation tool for a proper use of new modern food supplements in different conditions of use.